David S. Miller, Ph.D.
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Visiting Faculty, NIEHS
Membrane Biology
Environmental Stress Biology
B.S., Brooklyn College, Chemistry, 1966
Ph.D., University of Maine, Animal Nutrition/Biochemistry, 1973
Acting Chief, Laboratory of Pharmacology
Acting Chief, Laboratory of Molecular Toxicology
Acting Director, Environmental Toxicology Program
NIH/NIEHS
Transport proteins within specialized barrier and excretory tissues are major determinants of the uptake, distribution, and excretion of potentially toxic foreign chemicals and thus provide major protective functions. We use marine models to characterize the molecular mechanisms involved and their regulation. Current projects are focused on ATP-driven, efflux pumps within renal proximal tubule and the blood-brain barrier.
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