The Mount Desert Island Stem Cell Symposium is a joint symposium
of the Mount Desert Island Biological Laboratory and The
Jackson Laboratory aimed at promoting the exchange of new
ideas in the field of stem cell research.
The 2008 symposium, Epigenetic Regulation of Stem Cells, will include research presentations on chromatin remodeling, DNA methylation, microRNAs, proteins, and other epigenetic factors that influence stem cell development, differentiation, and renewal.
All
interested scientists are welcome to preregister and attend.
Abstracts are invited. Funds are available to eligible trainees to cover registration, room and board. Travel funds are not available.
Organizers
David Barnes, PhD, MDI Biological Laboratory
Edward J. Benz, Jr., MD, MDIBL and The Dana Farber Cancer Institute
Paul Collodi, PhD, Purdue University
Jonathan Epstein, MD, MDIBL and Univ. Pennsylvania SOM
John N. Forrest, Jr., MD, MDI Biological Laboratory and Yale SOM
Barbara K. Knowles, PhD, The Jackson Laboratory
John B. Macauley, PhD, The Jackson Laboratory
Michael McKernan, MDI Biological Laboratory
Rajesh Rao, Yale University School of Medicine
Leonard Zon, MD, HHMI and Harvard Medical School
Session I RNAs and microRNAs
Alex Schier, Ph.D., Harvard University
Maren Auditorium, MDIBL Conference Center
1:00 pm
Welcome and Introduction John N. Forrest, Jr., M.D., Director, MDI Biological Laboratory
1:10 pm
Richard Young, Ph.D., Whitehead Institute, MIT Transcriptional Circuitry and Epigenetic Reprogramming in Stem Cells
Introduction by John N. Forrest, Jr., M.D.
2:00 pm
Randy Jirtle, Ph.D., Duke University Medical Center Epigenetics, imprinting and disease susceptibility
2:30 pm
Tom Maniatis, Ph.D., Harvard University Multilevel regulation of gene expression by microRNAs
3:00 pm
Louise Laurent, M.D., Ph.D., The Scripps Research Institute Epigenetic crossroads in embryonic stem cells
3:30 pm
Break
3:45 pm
David Scadden, M.D., Massachusetts General Hospital MicroRNA regulation of hematopoietic stem cells
4:15 pm
Alex Schier, Ph.D., Harvard University MicroRNAs and Morphogens
4:45 pm
Jun Lu, Ph.D., Yale University School of Medicine MicroRNA-mediated control of hematopoietic lineage specification
5:15 pm
Bruce Draper, Ph.D., University of California, Davis Zebrafish Oogonial Stem Cells
6:00 pm
Reception and Lobster Bake MDIBL Dining Hall
7:30 pm
Irving Weissman, M.D., Stanford University School of Medicine
Normal and neoplastic stem cells
Introduction by Leonard Zon, M.D.
Saturday, August 9
7:30 am
Blueberry Pancake Breakfast MDIBL Dining Hall
Session II Nuclear Reprogramming Kyuson Yun, Ph.D., Chair Maren Auditorium, MDIBL Conference Center
8:00 am
Rudolph Jaenisch, M.D., Whitehead Institute Stem cells, pluripotency and nuclear reprogramming
8:30 am
Alex Meissner, Ph.D., Harvard University Dissecting the mechanism of direct reprogramming
9:00 am
Kathrin Plath, Ph.D, UCLA School of Medicine Mechanism of transcription factor- induced repogramming
9:30 am
Mary Goll, Ph.D. , The Carnegie Institute Tissue-specific monitoring of transcriptional silencing in vivo
10:00 am
Break
10:15 am
Nathan Lawson, Ph.D., Univ. Massachusetts Medical School Using zinc finger nucleases to modify the genome
10:45 am
Shawn Holt, Ph.D., Medical College of Virginia at Virginia Commonwealth University Defining a role for telomeres and telomerase in adult stem cell biology and reprogramming
11:15 am
Peter Fraser, Ph.D., Babraham Institute Transcription and nuclear organization of the genome
12:00 pm
Lunch MDIBL Dining Hall
Session III Chromatin and post-translational factors in epigenetics Leonard Zon, M.D., Chair Maren Auditorium, MDIBL Conference Center
1:30 pm
Terry Magnuson, Ph.D., University of North Carolina Epigenetics, Chromatin remodeling and mammalian development
2:00 pm
Leonard Zon, M.D., HHMI, The Children's Hospital Chromatin factors and zebrafish
2:30 pm
Stuart Orkin, M.D., HHMI, Dana Farber Cancer Institute Role of PRC2 in ES and other stem cells
3:00 pm
Harvey Lodish, Ph.D., Whitehead Institute Purification and expansion of hematopoietic stem cells based on proteins expressed by a novel fetal liver stromal cell population
3:30 pm
Break
3:45 pm
Maarten Van Lohuizen Ph.D., Netherlands Cancer Institute Polycomb repressors controlling stem cell fate: Implications for cancer and development
Session IV DNA and Protein Methylation Leonard Zon, M.D., Chair Maren Auditorium, MDIBL Conference Center
4:15 pm
Yi Zhang, Ph.D., HHMI, University of North Carolina-Chapel Hill Role of histone methylation in stem cell self-renewal
4:45 pm
Yi Sun, Ph.D., UCLA School of Medicine DNA methyltransferase Dnmt3a antagonizes polycomb binding to poised differentiation genes
5:15 pm
Poster session Hor d'oeuvres/Cocktails Lawn, MDIBL Conference Center
6:15 pm
Barbeque MDIBL Dining Hall
Call for Abstracts
The Mount Desert Island Stem Cell Symposium invites abstracts on epigenetic regulation of stem cells, and other related research areas. Abstracts may cover a range of topics within stem cell biology, including technology development, comparative genomics, transplantation, and genetics.
Submitted abstracts may be considered for a platform or poster presentation or to be included in the symposium abstract volume. Abstracts are welcomed from faculty, and all trainees including postdoctoral fellows and students.
The abstract formatting rules for platform/poster
presentation are listed below.
DEADLINE: July 25, 2008
Poster Session
The poster session is a highlight of the symposium. It is
a wonderful opportunity for one-on-one scientific interaction
and networking. All participants, even those giving platform
presentations, are encouraged to present their research in
the poster session. We expect a large crowd, lively conversation,
and refreshments.
Or, c ontact MDIBL conference
staff for accommodation suggestions.
Free shuttle service to and from the
hotels will be provided. However, car rental is recommended. Driving
directions from Boston and Bangor to MDIBL are also
available.
Detailed travel information, including a campus map, is available on the MDIBL
Travel page.
Funds are available to support registration, room, and board for students and trainees wishing
to attend the symposium. On campus dormitory housing is available. Please contact Michael
McKernan for more information.
Abstract Submission Guidelines
Format
- Page limit = 1 page
- MS Word, plain text, or PDF file format only.
Style
- Font size: 12, Type Style: Times, Spacing:
single spaced copy using paragraph indents, Margins: 1".
- Double space between paragraphs and justify right margin.
Layout
- Title: The title of the abstract should
be bolded.
- Abbreviations must not be used in title.
- Name(s)/institution(s): List the author's name(s), institution(s)
where the work originated, city, state and country. Indicate
the SURNAME of each author followed by his or her INITIALS
only.
Please underline attending authors name. Double space after
affiliations and before the body text.
Contact
Information
Michael
McKernan Director, Education and
Conferences
MDI Biological Laboratory
PO Box 35
Salisbury Cove, ME 04672
207-288-9880 ext 100
