MDI Stem Cell Symposium

Comparative Models in Stem Cell Research: Perspectives on Cells and Disease

A symposium for stem cell researchers, developmental biologists, students and trainees who utilize or plan to utilize mammalian or fish models in stem stem cell research.

Summary

The Mount Desert Island Stem Cell Symposium is a joint symposium of the Mount Desert Island Biological Laboratory and The Jackson Laboratory aimed at promoting the exchange of new ideas in the field of stem cell research. The 2006 Symposium will examine current research in particular cell types, diseases, and therapies in comparative species including mammals, fish, birds, and invertebrates. The focus of the meeting is the role of stem cells; however, speakers will cover a range of topics including technology development, comparative genomics, transplantation, and genetics. All interested scientists are welcome to preregister and attend. Students are invited to attend at a reduced rate, and in addition, funds for travel and registration may be available. The symposium will immediately follow a companion workshop “Methods in Human Embryonic Stem Cell Research,” held at The Jackson Laboratory, August 6-11, 2006.

Organizers

David Barnes, PhD, MDI Biological Laboratory
Edward J. Benz, Jr., MD, MDIBL and The Dana Farber Cancer Institute
Paul Collodi, PhD, Purdue University
Jonathan Epstein, MDIBL and Univ. Pennsylvania SOM
John N. Forrest, Jr., MD, MDI Biological Laboratory and Yale SOM
Barbara K. Knowles, PhD, The Jackson Laboratory
John B. Macauley, PhD, The Jackson Laboratory
Michael McKernan, MDI Biological Laboratory
Rajesh Rao, Yale University School of Medicine
Leonard Zon, MD, HHMI and Harvard Medical School

Symposium Schedule (updated August 11, 2006)

Friday, August 11
11:00 am - 1:00 pm	Registration MDIBL Conference Center
12:00 pm - 1:00 pm	Lunch MDIBL Dining Hall
Session I Current Topics in Embryonic Stem Cell Research Maren Auditorium, MDIBL Conference Center
1:00 pm	Welcome and Introduction John N. Forrest, Jr., MD, Director, MDI Biological Laboratory
1:10 pm	John Gearhart, MD, Johns Hopkins Medical Institute Differentiation of ES cells: Basic science to cell-based interventions
1:30 pm	Peter Andrews, PhD, University of Sheffield International Stem Cell Initiative Summary: Jax Human ES Cell Workshop
1:50 pm	Jose Cibelli, DVM, Michigan State University Nuclear transfer cloning and parthenogenesis
2:10 pm	Stuart Orkin, MD, HHMI and Dana-Farber Cancer Institute A protein network for pluripotency in ES cells
2:30 pm	Shawn Holt, PhD, Medical College of Virginia at Virginia Commonwealth University Functional Conservation of Telomerase, from Marine Animals to Humans
2:50 pm	Paul Collodi, PhD, Purdue University Zebrafish primordial germ cell cultures established from transgenic embryos by drug selection
3:10 pm	Break
Session 2 Genetics of Stem Cells Maren Auditorium, MDIBL Conference Center
3:45 pm	Louis Kunkel, PhD, HHMI, The Children's Hospital Human neuromuscular disease
4:15 pm	Elwood Linney, PhD, Duke University Medical Center Challenging the zebrafish embryonic nervous system--molecular and adult repercussions
4:35 pm	Shannon Fisher, PhD, Johns Hopkins University School of Medicine Unraveling transcriptional regulation of mammalian development in transgenic zebrafish
4:55 pm	Tom Look, MD, Dana-Farber Cancer Institute Genetic models of leukomogenesis
5:15 pm	James Petitte, PhD, North Carolina State University Avian Embryonic Stem Cells, Primordial Germ Cells and Transgenic Chickens
6:00 pm	Reception and Lobster Bake
6:30 pm	Dinner
7:30 pm	John Gearhart, Ph.D. Michael C. Armstrong Professor of Medicine Director, Stem Cell Program Institute for Cell Engineering Johns Hopkins Medical Institute Who turned out the enlightenment?

Saturday, August 12
7:30 am	Blueberry Pancake Breakfast MDIBL Dining Hall
Session 3 Neural Stem Cells Maren Auditorium, MDIBL Conference Center
8:30 am	Derek Van Der Kooy, PhD, The University of Toronto The neural stem cell lineage
9:00 am	Ava Udvadia, PhD, University of Wisconsin-Milwaukee Gene Expression Regulating Axon Growth Capability in Developing, Maturing, and Regenerating Neurons: A Comparative Genomics Approach
9:20 am	Barbara Beltz, PhD, Wellelsley College Adult neurogenesis: A common strategy across diverse species
9:40 am	Evan Snyder, MD, PhD, The Burnham Institute Is there a role for stem cells in therapies against brain tumors?
10:00 am	Arturo Alvarez-Bullya, PhD, University of San Francisco Adult neural stem cells and tumors
10:20 am	Break
Session 4 Stem Cells and Hematology Maren Auditorium, MDIBL Conference Center
10:40 am	Diane Krause, MD, PhD, Yale University School of Medicine Epithelial differentiation of bone marrow derived cells
11:10 am	David Traver, PhD, University of California - San Diego Hematopoietic stem and progenitor cells in the zebrafish
11:30 am	Leonard Zon, MD, HHMI and The Children's Hospital-Boston Induction of Hematopoietic Stem Cells in Zebrafish
11:50 am	Yuichi Niikura, PhD, Massachusetts General Hospital Long-term Effects of Bone Marrow Transplantation on Oogenesis and Fertility in Chemotherapy-conditioned Adult Female Mice
12:10 pm	Nathan Lawson, PhD, Univ. Massachusetts Medical School Cell fate choice during blood vessel development in the zebrafish
12:30 pm	Lunch
Session 5 Differentiation and Patterning Maren Auditorium, MDIBL Conference Center
2:00 pm	Marnie Halpern, PhD, Carnegie Inst. of Washington Generating left-right differences in the zebrafish brain
2:20 pm	Mary Mullins, PhD, University of Pennsylvania School of Medicine Establishment of oocyte polarity in vertebrates
2:40 pm	Pamela Raymond, PhD, University of Michigan Retinal neurogenesis
3:00 pm	Stephen Johnson, PhD, Washington Univ. Medical School Pigment pattern and fin development
3:20 pm	Break
3:40 pm	Iain Drummond, PhD, Massachusetts General Hospital Differentiation of renal sub-types
4:00 pm	Wolfram Goessling, MD, PhD, The Children's Hospital - Boston WNT signaling mediates early liver growth and endodermal fate decisions
4:20 pm	Clarissa Henry, PhD, The University of Maine Muscle Fiber and Myotome Boundary Morphogenesis in Zebrafish
5:30 pm	Poster session Hor d'oeuvres/Cocktails Lawn, MDIBL Conference Center
6:00 pm	Banquet Lawn, MDIBL Conference Center
7:00 pm	After dinner speaker, Dr. John Gearhart Lawn, MDIBL Conference Center

Registration and Fees

Includes registration and all meals
Academic / Gov't.	$375
Corporate	$455
Student	$125
Registration closed. Please call the MDIBL Courses and Conferences office if you wish to attend this symposium.

The MDIBL Business Office will send an invoice when you pre-register.

Accommodations and Travel

Rooms have been blocked at the following hotels. Please refer to the MDI Stem Cell Symposium when making a reservation.

August is the height of tourist season on Mount Desert Island, so an early reservation is essential. Rooms not reserved will be released on July 1st. Reserve your room by June 31st or earlier. Undergraduate and graduate students may request housing on the MDIBL campus for a reduced rate. Limited availibility.

On-campus	Students receive priority	207-288-9880 ext 108
Best Western Inn	~15 min walk	207-288-5823	$90- 116
Bar Harbor Regency	~10 min drive (in-town Bar Harbor)	207-288-8983	$189-239
Eden House	~10 min drive (in-town Bar Harbor)	207-288-8983	$155

Contact MDIBL conference staff for other accommodation suggestions.

Free shuttle service to and from the hotels will be provided. However, car rental is recommended. Driving directions from Boston and Bangor to MDIBL are also available.

Detailed travel information is available on the MDIBL Travel page.

The Bar Harbor Chamber of Commerce has information regarding local attractions, including Acadia National Park.

Student Funding

Funds are available to support travel, housing, and registration fees for students and trainees wishing to attend the symposium. Please contact Michael McKernan for more information.

Contact Information

Michael McKernan
Director, Education and Conferences
MDI Biological Laboratory
PO Box 35
Salisbury Cove, ME 04672
207-288-9880 ext 100

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